Markovnikov's and anti-Markovnikov's addition are two types of electrophilic addition reactions that occur in organic chemistry. The main difference between the two is the regiochemistry of the reaction, which refers to the position of the added group relative to the double bond. Markovnikov's addition occurs when the electrophile adds to the carbon atom of the double bond that has more hydrogen atoms attached to it, while anti-Markovnikov's addition occurs when the electrophile adds to the carbon atom of the double bond that has fewer hydrogen atoms attached to it. In other words, Markovnikov's addition follows the rule "the rich get richer," while anti-Markovnikov's addition follows the rule "the poor get richer." The difference in regiochemistry is due to the formation of a more stable carbocation intermediate in Markovnikov's addition, which leads to preferential attachment of the electrophile to the more substituted carbon atom. Anti-Markovnikov's addition is less common than Markovnikov's addition and usually requires special conditions or reagent.
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